Journal Articles

2020's
  1. B.M. King, J. Fiegel. Zwitterionic polymer coatings enhance gold nanoparticle stability and uptake in various biological environments. The AAPS J. 2021; accepted.
  2. K.V. Tobin, J. Fiegel, N.K. Brogden. Thermosensitive gels used to improve microneedle assisted transdermal delivery of naltrexone. Polymers. 2021; 13: 933.
  3. J. Fiegel, B. Rundlett, A. Bradley, K. Murhammer. Piloting an ethics choose-your-own adventure activity in early engineering education. Paper presented at 2021 ASEE Annual Conference and Exhibition. Long Beach, CA.
  4. J. Russo, J. Fiegel, N.K. Brogden. Rheological and drug delivery characteristics of poloxamer-based diclofenac sodium formulations for chronic wound site analgesia. Pharmaceutics. 2020; 12(12): 1214.
  5. R. Hamed, D. Schenck, J. Fiegel. Surface rheological properties alter aerosol formation from mucus mimetic surfaces. Soft Matter. 2020; 16, 7823-7834. DOI: 10.1039/D0SM01232G.
  6. A.T. Ogunjimi, J. Fiegel, N.K. Brogden. Design and characterization of spray dried chitosan naltrexone microspheres for microneedle-assisted transdermal delivery. Pharmaceutics. 2020; 12: 496.
  7. R. Smith, J. Russo, J. Fiegel, N. Brogden. Antibiotic delivery strategies to treat skin infections when innate antimicrobial defense fails. Antibiotics. 2020; 9:56.
  8. B.M. King, N.J. Janechek, N. Bryngelson, A. Adamcakova-Dodd, T. Lersch, K. Bunker, G. Casuccio, P.S. Thorne, C.O. Stanier, J. Fiegel. Lung cell exposure to secondary photochemical aerosols generated from OH oxidation of cyclic siloxanes. Chemosphere. 2020; 241: 125126.
2010's
  1. D. Schenck, S. Goettler, J. Fiegel. Surfactant-induced spreading of nanoparticles is inhibited on mucus mimetic surfaces that model native lung conditions. Physical Biology. 2019; 16(6):065001.
  2. B. Givens, E. Wilson, J. Fiegel. The effect of salts in aqueous media on the formation of the BSA corona on SiO2 nanoparticles. Colloids Surf. B. 2019; 179: 374-381.
  3. B.E. Givens, N.D. Diklich, J. Fiegel, V.H. Grassian. Adsorption of bovine serum albumin on silicon dioxide nanoparticles: Impact of pH on nanoparticle-protein interactions. Biointerfaces. 2017; 12, 02D404.
  4. S. Sommerfeld Ross, S. Gharse, L. Sanchez, J. Fiegel. Dry powder aerosols to co-deliver antibiotics and nutrient dispersion compounds for enhanced bacterial biofilm eradication. Int. J. Pharm. 2017; 531(1): 14-23.
  5. B.E. Givens, Z. Xu, J. Fiegel, V.H. Grassian. Bovine serum albumin adsorption on SiO2 and TiO2 nanoparticle surfaces at circumneutral and acidic pH: A tale of two nano-bio surface interactions. J. Colloid Interface Sci. 2017; 493: 334-341.
  6. D. Schenck, J. Fiegel. Tensiometric and phase domain behavior of lung surfactant on mucus-like viscoelastic hydrogels. ACS Applied Materials & Interfaces. 2016; 8(9): 5917-5928.
  7. S. Gharse, J. Fiegel. Large porous hollow particles: Lightweight champions of pulmonary drug delivery. Current Pharmaceutical Design. 2016; 22(17): 2463-2469.
  8. A. Farnoud, J. Fiegel. Calf lung surfactant recovers surface functionality after exposure to aerosols containing polymeric particles. J. Aerosol Med. Pulm. Drug Deliv. 2016; 29(1): 10-23.
  9. S.R. Kwon, D.V. Dawson, D.M. Schenck, J. Fiegel, P.W. Wertz. Spectrophotometric evaluation of potassium nitrate penetration into the pulp cavity. Operative Dentistry. 2015; 40(6): 614-621.
  10. S. Sommerfeld Ross, M.H. Tu, M.L. Falsetta Wood, M.R. Ketterer, M.R. Kiedrowski, A.R. Horswill, M.A. Apicella, J.M. Reinhardt, J. Fiegel. Quantification of confocal images of biofilms grown on irregular surfaces. J. Microbiol. Methods. 2014; 100: 111-120.
  11. R. Hamed, J. Fiegel. Synthetic tracheal mucus with native rheological and surface tension properties. J. Biomed. Mater. Res. Part A. 2014; 102(6): 1788-1798.
  12. A. Farnoud, J. Fiegel. Interaction of dipalmitoyl phosphatidylcholine monolayers with a particle-laden subphase. J. Phys. Chem. B. 2013; 117(40): 12124-12134.
  13. E.D. Oldham, S. Seelam, C.F. Lema, R.J. Aguilera, J. Fiegel, S.E. Rankin, B.L. Knutson, H.-J. Lehmler. Synthesis, surface properties and biocompatibility of 1,2,3-triazoles containing alkyl beta-D-xylopyranoside surfactants. Carbohydrate Chemistry. 2013; 379: 68-77.
  14. R. Hamed, J. Fiegel. Synthetic Tracheal Mucus with Native Rheological and Surface Tension Properties. J. Biomed. Mater. Res. Part A. 2013:00A: 000-000 (published online: 29 JUN 2013, DOI: 10.1002/jbm.a.34851).
  15. A. Farnoud, J. Fiegel. Low concentrations of negatively charged sub-micron particles alter the microstructure of DPPC at the air-water interface. Colloid. Surface. A. 2012. 415(5): 320-327.
  16. S. Sommerfeld Ross, J. Fiegel. Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. Int. J. Antimicrob. Agents 2012. 40: 177-181.
  17. S. Sommerfeld Ross, J.M. Reinhardt, J. Fiegel. Enhanced analysis of bacteria susceptibility in connected biofilms. J. Microbiol. Methods 2012. 90(1): 9-14.
  18. E.D. Oldham, W. Xie, A.M. Farnoud, J. Fiegel, H.-J. Lehmler. Disruption of phosphatidylcholine monolayers and bilayers by perfluorobutanesulfonate. J. Phys. Chem. B 2012. 116: 9999-10007.
  19. J.S. Patton, J.D. Brain, L.A. Davies, J. Fiegel, M. Gumbleton, K.-J. Kim, M. Sakagami, R. Vanbever, C. Ehrhardt. The particle has landed - Characterizing the fate of inhaled pharmaceuticals. J. Aerosol Med. Pulm. Drug Deliv. 2010. 23(S2): S71-S87.
  20. S. Ross, E. Thomas, B. Stohs, J. Fiegel. Treating lung biofilm infections: Dispersion and eradication of dry powder aerosols. Respir. Drug Deliv. 2010. 3: 813-817.
2000's
  1. J. Fiegel, L. Garcia-Contreras, M. Thomas, J. VerBerkmoes, A. Hickey, D. Edwards. Preparation and in vivo evalaution of a dry powder for inhalation of capreomycin. Pharm. Res.. 2008; 25(4):805-811.
  2. L. Garcia-Contreras, J. Fiegel, M.J. Telko, K. Elbert, A. Hawi, M. Thomas, J. VerBerkmoes, W.A. Germishuizen, P.B. Fourie, A.J. Hickey, D. Edwards. Inhaled large porous particles of capreomycin for the treatment of tuberculosis in a guinea pig model. Antimicrob. Agents Chemother.. 2007; 51(8):2830-2836.
  3. J. Fiegel, R. Clarke, D. Edwards. Airborne infectious disease and the suppression of exhaled aerosols [review]. Drug Discovery Today. 2006; 11(1-2):51-57.
  4. W. Watanabe, M. Thomas, R. Clarke, A. Klibanov, R. Langer, G. Fuller, J. Fiegel, D. Edwards. Why inhaling salt water changes what we exhale. J. Colloid Interface Sci.. 2007; 307(1):71-78.
  5. D.A. Edwards, J. Fiegel, W. DeHaan, M. Brande, J. Man, R. Clarke. Novel inhalants for control and protection against airborne infections [review]. Respiratory Drug Delivery 2006; 1:  41-48.
  6. J. Fiegel, F. Jin, J. Hanes, K. Stebe. Wetting of a particle in a thin film. J. Colloid Interface Sci. 2005; 291(2):507-514.
  7. J. Fiegel, J. Fu, J. Hanes. Poly(ether-anhydride) microparticle aerosolization improved by controlling particle surface properties. J. Control. Release. 2004; 96(3):411-423.
  8. J. Fu, J. Fiegel, J. Hanes. Synthesis and characterization of PEG-based ether-anhydride terpolymers: Novel polymers for pulmonary drug delivery. Macromolecules; 2004. 37(19): 7174-7180.
  9. J. Fiegel, C. Ehrhardt, U.F. Schaefer, C.-M. Lehr, J. Hanes. Large porous particle impingement on lung epithelial cell monolayers: Toward improved particle characterization in the lung. Pharm. Res. 2003; 20(5):788-796.
  10. J. Fu, J. Fiegel, E. Krauland, J. Hanes. New polymer carriers for pulmonary drug delivery. Biomaterials 2002; 23(22):4425-4433.
  11. C. Ehrhardt, J. Fiegel, S. Fuchs, R. Abu-Dahab, U.F. Schaefer, J. Hanes, C.-M. Lehr. Drug absorption by the respiratory mucosa – Cell culture models and particulate drug carriers. J. Aerosol Med. 2002; 15(2):131-139.
  12. C. Ehrhardt, C. Kneuer, J. Fiegel, J. Hanes, U.F. Schaefer, K.-J. Kim, C.-M. Lehr. Influence of apical fluid volume on the development of functional cellular junctions in the human bronchial epithelial cell line 16HBE14o-: implications for the use as an in vitro model for drug absorption. Cell & Tissue Research 2002; 308:391-400.

Book Chapters

  1. S. Gharse, J. Fiegel. Cystic Fibrosis Infection and Biofilm Busters. In: H. Mansour and A. Hickey (eds.) Inhalation Aerosols: Physical and Biological Basis for Therapy: InformaHealthCare/CRC Press/Taylor & Francis. 2018.
  2. T. Brenza, R. Hamed, and J. Fiegel. Controlled transport for pulmonary drug delivery. In: H. Smyth and A. Hickey (eds.) Controlled Release Science and Technology: Pulmonary Delivery, New York: Springer. 2011.
  3. J. Hanes, M. Dawson, Y. Har-el, J. Suh, and J. Fiegel. Gene Therapy in the Lung. In: A. J. Hickey (ed.) Pharmaceutical Inhalation Aerosol Technology, 2nd edition. Vol. 134. New York: Marcel Dekker Inc. 2003.
Patents
  1. J. Hanes, J. Fiegel, and J. Fu. Biodegradable polymer compositions: Compositions and uses related thereto, US20030086895, EP, AU, WO.
  2. J. Fiegel, J. Sung, D. Edwards. Particles for Treatment of Pulmonary Infection. US20080213373, BR, ZA, MX, EP, CA, IN, WO, CN.