Journal Articles:
- D. Schenck, S. Goettler, J. Fiegel. Surfactant-induced
spreading of nanoparticles is inhibited on mucus mimetic surfaces that model
native lung conditions. Physical Biology,
16(6):065001 (2019).
- B.E. Givens, N.D. Diklich, J. Fiegel, V.H.
Grassian. Adsorption of bovine serum albumin on silicon dioxide nanoparticles:
Impact of pH on nanoparticle-protein interactions. Biointerfaces. 12, 02D404 (2017).
- S. Sommerfeld Ross, S. Gharse, L. Sanchez, J.
Fiegel. Dry powder aerosols to co-deliver antibiotics and nutrient
dispersion compounds for enhanced bacterial biofilm eradication. Int. J. Pharm. 2017; 531(1): 14-23.
- B.E. Givens, Z. Xu, J. Fiegel, V.H.
Grassian. Bovine serum albumin adsorption on SiO2 and TiO2
nanoparticle surfaces at circumneutral and acidic pH: A tale of two nano-bio
surface interactions. J. Colloid Interface Sci. 2017; 493: 334-341.
- D. Schenck, J. Fiegel. Tensiometric and
phase domain behavior of lung surfactant on mucus-like viscoelastic hydrogels. ACS Applied Materials & Interfaces. 2016;
8(9): 5917-5928.
- S. Gharse, J. Fiegel. Large porous hollow
particles: Lightweight champions of pulmonary drug delivery. Current Pharmaceutical Design. 2016;
22(17): 2463-2469.
- A. Farnoud, J. Fiegel. Calf lung
surfactant recovers surface functionality after exposure to aerosols containing
polymeric particles. J. Aerosol Med.
Pulm. Drug Deliv. 2016; 29(1): 10-23.
- S.R. Kwon, D.V. Dawson, D.M. Schenck, J.
Fiegel, P.W. Wertz. Spectrophotometric evaluation of potassium nitrate
penetration into the pulp cavity. Operative
Dentistry. 2015; 40(6): 614-621.
- S. Sommerfeld Ross, M.L.
Falsetta Wood, M.A. Apicella, J.M. Reinhardt, J. Fiegel. Quantification
of confocal images of biofilms grown on irregular surfaces. J. Microbiol. Methods. 2014; 100: 111-120.
- A. Farnoud, J. Fiegel. Interaction of dipalmitoyl phosphatidylcholine monolayers with a particle-laden subphase. J. Phys. Chem. B. 2013; 117(40): 12124-12134.
- E.D. Oldham, S. Seelam, C.F. Lema, R.J. Aguilera, J. Fiegel, S.E. Rankin, B.L. Knutson, H.-J. Lehmler.
Synthesis, surface properties and biocompatibility of 1,2,3-triazoles containing alkyl beta-D-xylopyranoside surfactants. Carbohydrate Chemistry. 2013; 379: 68-77.
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R. Hamed, J. Fiegel.
Synthetic Tracheal Mucus with Native Rheological and Surface Tension Properties. J. Biomed. Mater. Res. Part A. 2014; 102(6): 1788-1798.
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A. Farnoud, J. Fiegel.
Low concentrations of negatively charged sub-micron particles alter the microstructure of DPPC at the air-water interface. Colloid. Surface. A. 2012. 415(5): 320-327.
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S. Sommerfeld Ross, J. Fiegel.
Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. Int. J. Antimicrob. Agents 2012. 40: 177-181.
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S. Sommerfeld Ross, J.M. Reinhardt, J. Fiegel.
Enhanced analysis of bacteria susceptibility in connected biofilms. J. Microbiol. Methods 2012. 90(1): 9-14.
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E.D. Oldham, W. Xie, A.M. Farnoud, J. Fiegel, H.-J. Lehmler.
Disruption of phosphatidylcholine monolayers and bilayers by perfluorobutanesulfonate. J. Phys. Chem. B 2012. 116: 9999-10007.
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J.S. Patton, J.D. Brain, L.A. Davies, J. Fiegel, M. Gumbleton, K.-J. Kim, M. Sakagami, R. Vanbever, C. Ehrhardt.
The particle has landed - Characterizing the fate of inhaled pharmaceuticals. J. Aerosol Med. Pulm. Drug Deliv. 2010. 23(S2): S71-S87.
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S. Ross, E. Thomas, B. Stohs, J. Fiegel.
Treating lung biofilm infections: Dispersion and eradication of dry powder aerosols. Respir. Drug Deliv. 2010. 3: 813-817.
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J. Fiegel, L. Garcia-Contreras, M. Thomas, J. VerBerkmoes, A. Hickey, D. Edwards.
Preparation and in vivo evalaution of a dry powder for inhalation of capreomycin. Pharm. Res.. 2008; 25(4):805-811.
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L. Garcia-Contreras, J. Fiegel, M.J. Telko, K. Elbert, A. Hawi,
M. Thomas,
J. VerBerkmoes, W.A. Germishuizen, P.B. Fourie, A.J. Hickey, D. Edwards.
Inhaled large porous particles of capreomycin for the treatment of
tuberculosis in a guinea pig model. Antimicrob. Agents Chemother.. 2007; 51(8):2830-2836.
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J. Fiegel, R. Clarke, D. Edwards.
Airborne infectious disease and the suppression of exhaled aerosols [review]. Drug Discovery Today. 2006; 11(1-2):51-57.
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W. Watanabe, M. Thomas, R. Clarke, A. Klibanov, R. Langer,
G. Fuller, J. Fiegel, D. Edwards. Why inhaling salt water changes what we exhale. J. Colloid Interface Sci.. 2007; 307(1):71-78.
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D.A. Edwards, J. Fiegel, W. DeHaan, M. Brande, J.
Man, R. Clarke. Novel inhalants for control and protection against airborne infections [review]. Respiratory Drug Delivery 2006; 1: 41-48.
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J. Fiegel, F.
Jin, J. Hanes, K. Stebe. Wetting of a particle in a thin film. J. Colloid Interface Sci. 2005; 291(2):507-514.
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J. Fiegel, J. Fu, J. Hanes. Poly(ether-anhydride) microparticle aerosolization improved by controlling particle surface
properties. J. Control. Release. 2004; 96(3):411-423.
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J. Fu, J. Fiegel, J. Hanes. Synthesis and characterization
of PEG-based ether-anhydride terpolymers: Novel polymers for pulmonary drug delivery. Macromolecules; 2004. 37(19): 7174-7180.
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J. Fiegel, C. Ehrhardt, U.F. Schaefer, C.-M. Lehr, J. Hanes.
Large porous particle impingement on lung epithelial cell monolayers:
Toward improved particle characterization in the lung. Pharm. Res. 2003; 20(5):788-796.
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J. Fu, J. Fiegel, E. Krauland, J. Hanes. New polymer carriers for pulmonary drug delivery. Biomaterials 2002; 23(22):4425-4433.
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C. Ehrhardt, J. Fiegel, S. Fuchs, R. Abu-Dahab, U.F. Schaefer, J. Hanes, C.-M. Lehr. Drug absorption
by the respiratory mucosa – Cell culture models and particulate drug carriers. J. Aerosol Med. 2002; 15(2):131-139.
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C. Ehrhardt, C. Kneuer, J. Fiegel, J. Hanes, U.F. Schaefer, K.-J.
Kim, C.-M. Lehr. Influence
of apical fluid volume on the development of functional cellular
junctions in the human bronchial epithelial cell line 16HBE14o-:
implications for
the use as an in vitro model for drug absorption. Cell & Tissue Research 2002; 308:391-400.
Book Chapters:
- S. Gharse, J. Fiegel. Cystic Fibrosis Infection and Biofilm Busters.
In: H. Mansour and A. Hickey
(eds.) Inhalation Aerosols: Physical and Biological Basis for Therapy: InformaHealthCare/CRC Press/Taylor & Francis. 2018.
- T. Brenza, R. Hamed, and J. Fiegel. Controlled transport for pulmonary drug delivery. In: H. Smyth and A. Hickey (eds.) Controlled Release Science and Technology: Pulmonary Delivery, New York: Springer. 2011.
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J. Hanes, M. Dawson, Y. Har-el, J. Suh, and J. Fiegel. Gene Therapy in the Lung. In: A. J. Hickey (ed.) Pharmaceutical Inhalation Aerosol
Technology, 2nd edition. Vol. 134. New York: Marcel Dekker Inc. 2003.
Patents:
-
J. Hanes, J. Fiegel, and J. Fu. Biodegradable polymer
compositions: Compositions and uses related thereto, U.S. Patent No.
7,163,697 B2. Granted January 16, 2007.
- J.
Fiegel,
J. Sung, D. Edwards. Particles for Treatment of Pulmonary
Infection. U.S. Patent No. 8,846,607. Granted September 30, 2014; Canadian Patent No. 2,585,859.
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